課程資訊
課程名稱
後生遺傳學
Epigenetics 
開課學期
103-1 
授課對象
生物資源暨農學院  生物科技研究所  
授課教師
林劭品 
課號
Biot8001 
課程識別碼
642ED0020 
班次
 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一5,6,7(12:20~15:10) 
上課地點
生技所415 
備註
本課程以英語授課。與林詩舜合開
限博士班
總人數上限:20人
外系人數限制:15人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1031Biot8001_Epigene 
課程簡介影片
 
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課程概述

Introduction–Epigenetic Overview
DNA methylation and genome defense
RNAi and heterochromatin
Evolution of mammalian epigenetic control systems
Epigenetics and development
Epigentics and human disease
X-inactivation
Genomic imprinting in mammals
Genomic imprinting in plants
Epignetics and reprogramming
Epigenetics in assisted reproductive techniques
Applied epigenetics: flowering plants and tissue engineering
 

課程目標
Course description: This graduate course aims to introduce basic epigenetic concepts and research techniques available to address epigenetic questions in mammals as well as other organisms. Students are expected to develop the ability to critically evaluating and interpreting published research articles. They will also learn to extract information from international conferences by listening to experts of each field introducing their research (as in the CD-ROM). 
課程要求
Basic knowledge in Molecular Biology 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
Open book midterm exam 
30% 
 
2. 
Discussion/ Presentation during the course 
50% 
Author/Reviewer role playing 
3. 
End of Term Paper Report 
20% 
 
 
課程進度
週次
日期
單元主題
第1週
9/15  SP Lin: Introduction of Epigenetics 
第2週
9/22  SP Lin: Physiological Epigenomic Reprogramming in Germ Cells and Preimplantationm Embryos 
第3週
9/29  Small RNA world in plant (1)_ SS Lin
+ X inactivation_SP Lin 
第4週
10/06  Small RNA world in plant (2)_SS Lin 
第5週
10/13  Long non-coding RNA and RdDM in plants_SS Lin 
第6週
10/20  SP Lin: Experimental Reprogramming and its implications in Regenerative Medicine 
第7週
10/27  SP Lin: Epigenetics in Physiological and Pathological Phenomenons 
第8週
11/03  Gene silencing and Autophagy_SS Lin 
第9週
11/10  Open Book Midterm exam (SP Lin/SS Lin) 
第10週
11/17  11/17 SP Lin
11/18 NTU Medical Campus: Prof. Cedar/Prof. 阮麗容/Prof. Shau-Ping Lin 
第11週
11/24  SP Lin_Epigenetic editing? 
第12週
12/01  SS Lin: Autophage and gene silencing 
第13週
12/08  Sp Lin: Epigenetic editing 
第14週
12/15  (SS Lin & SP Lin) Genetic editing & Epigenetic editing (Part II): Implication in Plant Biology and Agriculture
 
第15週
12/22  Students' show time: Cancer Epigenomics 
第16週
12/29  Students' show time:Epigenetics in Developments and in vitro Regeneration 
第17週
1/05  Students' show time: Tissue regeneration in various species 
第18週
1/12  Final report